CTOSD
A Center for the Treatment of Ocular Surface Disease (CTOSD) has been established under
the directorship of Dr. Edward J. Holland. Dr. Holland and his partner Dr. Michael L.
Nordlund have developed the CTOSD in collaboration with the Cincinnati Eye Institute, the
Department of Ophthalmology at the University of Cincinnati and the St. Elizabeth Hospital
in Edgewood, KY. The mission of the CTOSD is to provide expert clinical care for patients
with complicated ocular surface stem cell disorders, to further investigate the
pathogenesis of stem cell disease and to develop ever improving therapies. Currently, the
CTOSD is focusing on stem cell disease resulting from aniridia, thermal and chemical
injuries and inflammatory conditions such as Stevens Johnson Syndrome, ocular cicatricial
pemphigoid and atopic keratoconjunctivitis. Patients interested in scheduling an
evaluation with Dr. Holland or Dr. Nordlund can contact the CTOSD at the phone number and
address listed below.20
The CTOSD is conducting several scientific studies. Current basic science research
projects are directed at improving our understanding of the pathogenesis of limbal
abnormalities in aniridia and the response of stem cells to chemical and mechanical
injuries of the cornea. Several clinical studies are also in progress. One study is aimed
at more clearly defining the natural history of aniridia and its manifestations. This
study primarily involves reviewing charts of aniridic patients to chronical the
development of the manifestations of aniridia. Patients with aniridia can participate by
providing copies of their ophthalmic medical records. A second study that will be starting
in the near future involves evaluating aniridic limbal tissue with varying stages of
keratopathy. Patients undergoing stem cell transplantation will be eligible to participate
in this study. Patients interested in participating in these clinical investigations can
contact the CTOSD using the contact information below.
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Edward
J. Holland, MD
Michael L. Nordlund, MD,PhD
Center for the Treatment of Ocular Surface Disease
Cincinnati Eye Institiute
10494 Montgomery Road
Cincinnati, OH 45242
Phone (800) 984-5133
Fax (513) 984-4870 |
